Kommoss FKF, Stichel D, Schrimpf D, Kriegsmann M, Tessier-Cloutier B, Talhouk A, McAlpine JN, Chang KTE, Sturm D, Pfister SM, Romero-Pérez L, Kirchner T, Grünewald TGP, Buslei R, Sinn HP, Mechtersheimer G, Schirmacher P, Schmidt D, Lehr HA, Sahm F, Huntsman DG, Gilks CB, Kommoss F, von Deimling A, Koelsche C. DNA methylation-based profiling of uterine neoplasms: a novel tool to improve gynecologic cancer diagnostics. J Cancer Res Clin Oncol. 2020 Jan;146(1):97-104. doi: 10.1007/s00432-019-03093-w. Epub 2019 Nov 25. PubMed PMID: 31768620.

 

Kommoss F, Lehr HA. [Sex cord-stromal tumors of the ovary: Current aspects with a focus on granulosa cell tumors, Sertoli-Leydig cell tumors, and gynandroblastomas]. Pathologe. 2019 Feb;40(1):61-72. doi: 10.1007/s00292-018-0562-3. Review. German. PubMed PMID: 30659330.

 

Robustness of biomarker determination in breast cancer by RT-qPCR: impact of tumor cell content, DCIS and non-neoplastic breast tissue. Hartmann K, Schlombs K, Laible M, Gürtler C, Schmidt M, Sahin U, Lehr HA. Diagn Pathol. 2018 Oct 20;13(1):83. doi: 10.1186/s13000-018-0760-6.

 

Risk factors for positive resection margins of breast cancer tumorectomy specimen following breast-conserving surgery. Heiss N, Rousson V, Ifticene-Treboux A, Lehr HA, Delaloye JF. Horm Mol Biol Clin Investig. 2017 Dec 9;32(2). pii: /j/hmbci.2017.32.issue-2/hmbci-2017-0023/hmbci-2017-0023.xml. doi: 10.1515/hmbci-2017-0023.

 

TIE-2-expressing monocytes are lymphangiogenic and associate specifically with lymphatics of human breast cancer. Bron S, Henry L, Faes-Van't Hull E, Turrini R, Vanhecke D, Guex N, Ifticene-Treboux A, Marina Iancu E, Semilietof A, Rufer N, Lehr HA, Xenarios I, Coukos G, Delaloye JF, Doucey MA. Oncoimmunology. 2015 Aug 20;5(2):e1073882. 

 

Quality in pathology: how good is good? An introduction. Bosman FT, Lehr HA. Virchows Arch. 2016 Jan;468(1):1-4. doi: 10.1007/s00428-015-1896-3.. 

 

Communication skills in diagnostic pathology. Lehr HA, Bosman FT. Virchows Arch. 2016 Jan;468(1):61-7. doi: 10.1007/s00428-015-1848-y. Epub 2015 Oct 19.

 

Standardization for Ki-67 assessment in moderately differentiated breast cancer. A retrospective analysis of the SAKK 28/12 study. Varga Z, Cassoly E, Li Q, Oehlschlegel C, Tapia C, Lehr HA, Klingbiel D, Thürlimann B, Ruhstaller T. PLoS One. 2015 Apr 17;10(4):e0123435. doi: 10.1371/journal.pone.0123435. 

 

Angiogenic activity of breast cancer patients' monocytes reverted by combined use of systems modeling and experimental approaches. Guex N, Crespo I, Bron S, Ifticene-Treboux A, Faes-Van't Hull E, Kharoubi S, Liechti R, Werffeli P, Ibberson M, Majo F, Nicolas M, Laurent J, Garg A, Zaman K, Lehr HA, Stevenson BJ, Rüegg C, Coukos G, Delaloye JF, Xenarios I, Doucey MA. PLoS Comput Biol. 2015 Mar 13;11(3):e1004050. doi: 10.1371/journal.pcbi.1004050. 

 

TH9 cells that express the transcription factor PU.1 drive T cell-mediated colitis via IL-9 receptor signaling in intestinal epithelial cells. Gerlach K, Hwang Y, Nikolaev A, Atreya R, Dornhoff H, Steiner S, Lehr HA, Wirtz S, Vieth M, Waisman A, Rosenbauer F, McKenzie AN, Weigmann B, Neurath MF. Nat Immunol. 2014 Jul;15(7):676-86. doi: 10.1038/ni.2920. Epub 2014 Jun 8. Erratum in: Nat Immunol. 2015 Feb;16(2):214. 

 

In vitro and in vivo repair activities of undifferentiated and classically and alternatively activated macrophages. Enderlin Vaz da Silva Z, Lehr HA, Velin D. Pathobiology. 2014;81(2):86-93. doi: 10.1159/000357306. 

 

Instruction of haematopoietic lineage choices, evolution of transcriptional landscapes and cancer stem cell hierarchies derived from an AML1-ETO mouse model. Cabezas-Wallscheid N, Eichwald V, de Graaf J, Löwer M, Lehr HA, Kreft A, Eshkind L, Hildebrandt A, Abassi Y, Heck R, Dehof AK, Ohngemach S, Sprengel R, Wörtge S, Schmitt S, Lotz J, Meyer C, Kindler T, Zhang DE, Kaina B, Castle JC, Trumpp A, Sahin U, Bockamp E. EMBO Mol Med. 2013 Dec;5(12):1804-20. doi: 10.1002/emmm.201302661. 

 

TIE-2 and VEGFR kinase activities drive immunosuppressive function of TIE-2-expressing monocytes in human breast tumors. Ibberson M, Bron S, Guex N, Faes-van't Hull E, Ifticene-Treboux A, Henry L, Lehr HA, Delaloye JF, Coukos G, Xenarios I, Doucey MA. Clin Cancer Res. 2013 Jul 1;19(13):3439-49. doi: 10.1158/1078-0432.CCR-12-3181. 

 

Microfluidic processor allows rapid HER2 immunohistochemistry of breast carcinomas and significantly reduces ambiguous (2+) read-outs. Ciftlik AT, Lehr HA, Gijs MA. Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5363-8. doi: 10.1073/pnas.1211273110. 

 

The selective phosphodiesterase 4 inhibitor roflumilast and phosphodiesterase 3/4 inhibitor pumafentrine reduce clinical score and TNF expression in experimental colitis in mice. Rieder F, Siegmund B, Bundschuh DS, Lehr HA, Endres S, Eigler A. PLoS One. 2013;8(2):e56867. doi: 10.1371/journal.pone.0056867. 

 

Mitotic figure counts are significantly overestimated in resection specimens of invasive breast carcinomas.  Lehr HA, Rochat C, Schaper C, Nobile A, Shanouda S, Vijgen S, Gauthier A, Obermann E, Leuba S, Schmidt M, C CR, Delaloye JF, Simiantonaki N, Schaefer SC. Mod Pathol. 2013 Mar;26(3):336-42. doi: 10.1038/modpathol.2012.140. 

 

Tumor architecture exerts no bias on nuclear grading in breast cancer diagnosis.Mora B, Bombari D, Schaefer SC, Schmidt M, Delaloye JF, Mast F, Lehr HA. Virchows Arch. 2012 Oct;461(4):399-403. doi: 10.1007/s00428-012-1304-1. 

 

Board examination for anatomical pathology in Switzerland: two intense days to verify professional competence.Lehr HA, Moch H, Christen B, Safret A, Gugger M, Rössle M, von Gunten M, Lemoine R, Kurt AM, Caduff R, Walter A, Singer G, Luscieti P, Bannwart F, Genton CY. Virchows Arch. 2012 Jul;461(1):87-92. doi: 10.1007/s00428-012-1262-7. 

 

What was I thinking? Eye-tracking experiments underscore the bias that architecture exerts on nuclear grading in prostate cancer.Bombari D, Mora B, Schaefer SC, Mast FW, Lehr HA. PLoS One. 2012;7(5):e38023. doi: 10.1371/journal.pone.0038023. 

 

How reliable is Ki-67 immunohistochemistry in grade 2 breast carcinomas? A QA study of the Swiss Working Group of Breast- and Gynecopathologists.Varga Z, Diebold J, Dommann-Scherrer C, Frick H, Kaup D, Noske A, Obermann E, Ohlschlegel C, Padberg B, Rakozy C, Sancho Oliver S, Schobinger-Clement S, Schreiber-Facklam H, Singer G, Tapia C, Wagner U, Mastropasqua MG, Viale G, Lehr HA. PLoS One. 2012;7(5):e37379. doi: 10.1371/journal.pone.0037379. 

 

[Giant cell arteritis: etiological knowledge and diagnostic challenge for pathologists].Schaefer SC, Lehr HA.Pathologe. 2012 May;33(3):228-35. doi: 10.1007/s00292-011-1555-7. German. 

 

Intravital microscopy reveals endothelial dysfunction in resistance arterioles in Angiotensin II-induced hypertension.Schäfer SC, Pellegrin M, Wyss C, Aubert JF, Nussberger J, Hayoz D, Lehr HA, Mazzolai L. Hypertens Res. 2012 Aug;35(8):855-61. doi: 10.1038/hr.2012.58. 

 

A comprehensive analysis of human gene expression profiles identifies stromal immunoglobulin κC as a compatible prognostic marker in human solid tumors.Schmidt M, Hellwig B, Hammad S, Othman A, Lohr M, Chen Z, Boehm D, Gebhard S, Petry I, Lebrecht A, Cadenas C, Marchan R, Stewart JD, Solbach C, Holmberg L, Edlund K, Kultima HG, Rody A, Berglund A, Lambe M, Isaksson A, Botling J, Karn T, Müller V, Gerhold-Ay A, Cotarelo C, Sebastian M, Kronenwett R, Bojar H, Lehr HA, Sahin U, Koelbl H, Gehrmann M, Micke P, Rahnenführer J, Hengstler JG. Clin Cancer Res. 2012 May 1;18(9):2695-703. doi: 10.1158/1078-0432.CCR-11-2210. E

 

Informed consent: Biobank donors should have a say.Spencer B, Koutaissoff D, Lehr HA. Nature. 2012 Jan 25;481(7382):443. doi: 10.1038/481443c. 

 

Absence of ectopic epithelial inclusions in 3,904 axillary lymph nodes examined in sentinel technique.Iken S, Schmidt M, Braun C, Valentino A, Lehr HA, Schaefer SC. Breast Cancer Res Treat. 2012 Apr;132(2):621-4. doi: 10.1007/s10549-011-1923-2. 

 

A role for T-bet-mediated tumour immune surveillance in anti-IL-17A treatment of lung cancer.Reppert S, Boross I, Koslowski M, Türeci Ö, Koch S, Lehr HA, Finotto S. Nat Commun. 2011 Dec 20;2:600. doi: 10.1038/ncomms1609.

 

Interactions between cancer stem cells and their niche govern metastatic colonization.Malanchi I, Santamaria-Martínez A, Susanto E, Peng H, Lehr HA, Delaloye JF, Huelsken J. Nature. 2011 Dec 7;481(7379):85-9. doi: 10.1038/nature10694.

 

Inflammatory myofibroblastic tumor of the trachea with concomitant granulomatous lymph node lesions.Koch JA, Dorn P, Rausch T, Ris HB, Lehr HA, Schäfer SC. Case Rep Med. 2011;2011:151729. doi: 10.1155/2011/151729. 

 

Protein-binding microarray analysis of tumor suppressor AP2αtarget gene specificity.Kerschgens J, Renaud S, Schütz F, Grasso L, Egener-Kuhn T, Delaloye JF, Lehr HA, Vogel H, Mermod N. PLoS One. 2011;6(8):e22895. doi: 10.1371/journal.pone.0022895. 

 

Characterization of chromosomal instability in murine colitis-associated colorectal cancer.Gerling M, Glauben R, Habermann JK, Kühl AA, Loddenkemper C, Lehr HA, Zeitz M, Siegmund B. PLoS One. 2011;6(7):e22114. doi: 10.1371/journal.pone.0022114. 

 

What makes a good pathology report?Nobile A, Treboux A, Delaloye JF, Zaman K, Jeanneret-Sozzi W, Schaefer SC, Lehr HA. Eur J Cancer. 2011 Sep;47(14):2082-3. doi: 10.1016/j.ejca.2011.06.033. Epub 2011 Jul 19. 

 

Impact of donor and recipient IL28B rs12979860 genotypes on hepatitis C virus liver graft reinfection.Lange CM, Moradpour D, Doehring A, Lehr HA, Müllhaupt B, Bibert S, Bochud PY, Antonino AT, Pascual M, Farnik H, Shi Y, Bechstein WO, Moench C, Hansmann ML, Sarrazin C, Lötsch J, Zeuzem S, Hofmann WP. J Hepatol. 2011 Aug;55(2):322-7. doi: 10.1016/j.jhep.2010.10.037. 

 

Expression of E-selectin and vascular cell adhesion molecule-1 in so-called 'negative' appendices: first results to support the pathological diagnosis in borderline cases.Brochhausen C, Bittinger F, Schmitt VH, Kommoss F, Lehr HA, Heintz A, Kirkpatrick CJ. Eur Surg Res. 2010;45(3-4):350-5. doi: 10.1159/000321698.  

 

Local transient myocardial liposomal gene transfer of inducible nitric oxide synthase does not aggravate myocardial function and fibrosis and leads to moderate neovascularization in chronic myocardial ischemia in pigs.Abegunewardene N, Schmidt KH, Vosseler M, Dreher M, Keller T, Hoffmann N, Veit K, Petersen SE, Lehr HA, Schreiber LM, Gori T, Horstick G, Münzel T. Microcirculation. 2010 Jan;17(1):69-78. doi: 10.1111/j.1549-8719.2010.00002.x.

 

[Predictive value of Her2/neu expression/amplification for the targeted treatment of breast cancer].Lehr HA, Schaefer SC, Delaloye JF.Rev Med Suisse. 2009 Jul 15;5(211):1525-9. French.

 

Transplantation tolerance induced by regulatory T cells: in vivo mechanisms and sites of action.Golshayan D, Wyss JC, Abulker CW, Schaefer SC, Lechler RI, Lehr HA, Pascual M. Int Immunopharmacol. 2009 Jun;9(6):683-8. doi: 10.1016/j.intimp.2008.12.006. 

 

Cryopreservation of prostate cancer tissue during routine processing of fresh unfixed prostatectomy specimen: demonstration and validation of a new technique.Schäfer SC, Pfnür M, Yerly S, Fandel TM, Jichlinski P, Lehr HA. Prostate. 2009 Feb 1;69(2):191-7. doi: 10.1002/pros.20868.

 

Long-term outcome prediction by clinicopathological risk classification algorithms in node-negative breast cancer--comparison between Adjuvant!, St Gallen, and a novel risk algorithm used in the prospective randomized Node-Negative-Breast Cancer-3 (NNBC-3) trial.Schmidt M, Victor A, Bratzel D, Boehm D, Cotarelo C, Lebrecht A, Siggelkow W, Hengstler JG, Elsässer A, Gehrmann M, Lehr HA, Koelbl H, von Minckwitz G, Harbeck N, Thomssen C. Ann Oncol. 2009 Feb;20(2):258-64. doi: 10.1093/annonc/mdn590. 

 

Prognostic effect of epithelial cell adhesion molecule overexpression in untreated node-negative breast cancer.Schmidt M, Hasenclever D, Schaeffer M, Boehm D, Cotarelo C, Steiner E, Lebrecht A, Siggelkow W, Weikel W, Schiffer-Petry I, Gebhard S, Pilch H, Gehrmann M, Lehr HA, Koelbl H, Hengstler JG, Schuler M. Clin Cancer Res. 2008 Sep 15;14(18):5849-55. doi: 10.1158/1078-0432.CCR-08-0669.

 

The transcription factor NFATc2 controls IL-6-dependent T cell activation in experimental colitis.Weigmann B, Lehr HA, Yancopoulos G, Valenzuela D, Murphy A, Stevens S, Schmidt J, Galle PR, Rose-John S, Neurath MF. J Exp Med. 2008 Sep 1;205(9):2099-110. doi: 10.1084/jem.20072484. 

 

Endotoxin accelerates atherosclerosis independent of complement activation.Reifenberg K, Lehr HA, Fan J, Koike T, Wiese E, Küpper I, Sagban TA, Schaefer SC, Zähringer U, Torzewski M, Lackner KJ, Bhakdi S. Thromb Res. 2009 Feb;123(4):653-8. doi: 10.1016/j.thromres.2008.06.017. 

 

Do we truly see what we think we see? The role of cognitive bias in pathological interpretation.Fandel TM, Pfnür M, Schäfer SC, Bacchetti P, Mast FW, Corinth C, Ansorge M, Melchior SW, Thüroff JW, Kirkpatrick CJ, Lehr HA. J Pathol. 2008 Oct;216(2):193-200. doi: 10.1002/path.2395.

 

The humoral immune system has a key prognostic impact in node-negative breast cancer.Schmidt M, Böhm D, von Törne C, Steiner E, Puhl A, Pilch H, Lehr HA, Hengstler JG, Kölbl H, Gehrmann M. Cancer Res. 2008 Jul 1;68(13):5405-13. doi: 10.1158/0008-5472.CAN-07-5206.

 

Images in cardiovascular medicine. Sudden cardiac death due to triple vessel coronary dissection.Lunebourg A, Letovanec I, Eggenberger P, Lehr HA. Circulation. 2008 Apr 15;117(15):2038-40. doi: 10.1161/CIRCULATIONAHA.107.729228. N

 

The MRL mouse repairs both cryogenic and ischemic myocardial infarcts with scar.Grisel P, Meinhardt A, Lehr HA, Kappenberger L, Barrandon Y, Vassalli G. Cardiovasc Pathol. 2008 Jan-Feb;17(1):14-22. 

 

[From histology via genetic signature to an improved treatment of breast cancer patients].Lehr HA, Delaloye JF, Bosman FT. Rev Med Suisse. 2007 Oct 24;3(130):2382-4, 2386-8. French. 

 

Resistance of the internal mammary artery to restenosis: a histomorphologic study of various porcine arteries.Horstick G, Bierbach B, Schlindwein P, Abegunewardene N, Vosseler M, Bittinger F, Becker D, Lauterbach M, Lehr HA, Kempski O. J Vasc Res. 2008;45(1):45-53. 

 

[Pathology near the patient].Lehr HA, Bosman FT. Rev Med Suisse. 2007 Jul 18;3(119):1715-6. French. 

 

A case study on the proper use of human tissues for biomedical research at an academic pathology institution in Switzerland.Schäfer SC, Lehr HA. Pathobiology. 2007;74(4):259-63.

 

Interferon-gamma induces chronic active myocarditis and cardiomyopathy in transgenic mice.Reifenberg K, Lehr HA, Torzewski M, Steige G, Wiese E, Küpper I, Becker C, Ott S, Nusser P, Yamamura K, Rechtsteiner G, Warger T, Pautz A, Kleinert H, Schmidt A, Pieske B, Wenzel P, Münzel T, Löhler J. Am J Pathol. 2007 Aug;171(2):463-72. Epub 2007 Jun 7.

 

Intraoperative lymphatic mapping and sentinel node biopsy using hysteroscopy in patients with endometrial cancer.Delaloye JF, Pampallona S, Chardonnens E, Fiche M, Lehr HA, De Grandi P, Delaloye AB. Gynecol Oncol. 2007 Jul;106(1):89-93. Epub 2007 Apr 17.

 

Deficiency of glutathione peroxidase-1 accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice.Torzewski M, Ochsenhirt V, Kleschyov AL, Oelze M, Daiber A, Li H, Rossmann H, Tsimikas S, Reifenberg K, Cheng F, Lehr HA, Blankenberg S, Förstermann U, Münzel T, Lackner KJ. Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):850-7. 

 

Role of the progesterone receptor for paclitaxel resistance in primary breast cancer.Schmidt M, Bremer E, Hasenclever D, Victor A, Gehrmann M, Steiner E, Schiffer IB, Gebhardt S, Lehr HA, Mahlke M, Hermes M, Mustea A, Tanner B, Koelbl H, Pilch H, Hengstler JG. Br J Cancer. 2007 Jan 29;96(2):241-7. Epub 2007 Jan 9.

[Should we resect all premalignant breast lesions?].Delaloye JF, Lehr HA. Rev Med Suisse. 2006 Oct 25;2(84):2408-10, 2412-4. Review. French. 

 

Dynamic MR imaging of breast lesions: correlation with microvessel distribution pattern and histologic characteristics of prognosis.Teifke A, Behr O, Schmidt M, Victor A, Vomweg TW, Thelen M, Lehr HA. Radiology. 2006 May;239(2):351-60. 

 

A novel in vitro model for the study of plaque development in atherosclerosis.Dorweiler B, Torzewski M, Dahm M, Ochsenhirt V, Lehr HA, Lackner KJ, Vahl CF. Thromb Haemost. 2006 Jan;95(1):182-9.

 

[Change in pathology].Bosman FT, Lehr HA. Rev Med Suisse. 2005 Nov 30;1(43):2771. French.

 

Expression of multiple epigenetically regulated cancer/germline genes in nonsmall cell lung cancer.Grunwald C, Koslowski M, Arsiray T, Dhaene K, Praet M, Victor A, Morresi-Hauf A, Lindner M, Passlick B, Lehr HA, Schäfer SC, Seitz G, Huber C, Sahin U, Türeci O. Int J Cancer. 2006 May 15;118(10):2522-8.

 

Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin: a clinicopathologic study of 26 cases and review of the literature.Folpe AL, Mentzel T, Lehr HA, Fisher C, Balzer BL, Weiss SW. Am J Surg Pathol. 2005 Dec;29(12):1558-75. Review.

 

Paradoxical attenuation of leukocyte rolling in response to ischemia- reperfusion and extracorporeal blood circulation in inflamed tissue.Schäfer SC, Sehrt DN, Kamler M, Jakob H, Lehr HA. Am J Physiol Heart Circ Physiol. 2005 Jul;289(1):H330-5.

 

In vivo imaging of colitis and colon cancer development in mice using high resolution chromoendoscopy.Becker C, Fantini MC, Wirtz S, Nikolaev A, Kiesslich R, Lehr HA, Galle PR, Neurath MF.Gut. 2005 Jul;54(7):950-4.

 

Long-term prognostic significance of HER-2/neu in untreated node-negative breast cancer depends on the method of testing.Schmidt M, Lewark B, Kohlschmidt N, Glawatz C, Steiner E, Tanner B, Pilch H, Weikel W, Kölbl H, Lehr HA. Breast Cancer Res. 2005;7(2):R256-66. 

 

Frequent nonrandom activation of germ-line genes in human cancer.Koslowski M, Bell C, Seitz G,Lehr HA, Roemer K, Müntefering H, Huber C, Sahin U, Türeci O. Cancer Res. 2004 Sep 1;64(17):5988-93.

 

Microvascular in vivo assessment of reperfusion injury: significance of prostaglandin E(1) and I(2) in postischemic "no-reflow" and "reflow-paradox".Tauber S, Menger MD, Lehr HA. J Surg Res. 2004 Jul;120(1):1-11.

 

HER-2/neu-mediated regulation of components of the MHC class I antigen-processing pathway.Herrmann F, Lehr HA, Drexler I, Sutter G, Hengstler J, Wollscheid U, Seliger B. Cancer Res. 2004 Jan 1;64(1):215-20.

 

Switching off HER-2/neu in a tetracycline-controlled mouse tumor model leads to apoptosis and tumor-size-dependent remission.Schiffer IB, Gebhard S, Heimerdinger CK, Heling A, Hast J, Wollscheid U, Seliger B, Tanner B, Gilbert S, Beckers T, Baasner S, Brenner W, Spangenberg C, Prawitt D, Trost T, Schreiber WG, Zabel B, Thelen M, Lehr HA, Oesch F, Hengstler JG. Cancer Res. 2003 Nov 1;63(21):7221-31.

 

Infrequent early recanalization of greater saphenous vein after endovenous laser treatment.Proebstle TM, Gül D, Lehr HA, Kargl A, Knop J. J Vasc Surg. 2003 Sep;38(3):511-6.

 

Outcome analysis and rational management of enhancing lesions incidentally detected on contrast-enhanced MRI of the breast.Teifke A, Lehr HA, Vomweg TW, Hlawatsch A, Thelen M. AJR Am J Roentgenol. 2003 Sep;181(3):655-62.

 

Metabolic classification of human rectal adenocarcinomas: a novel guideline for clinical oncologists? Walenta S, Chau TV, Schroeder T, Lehr HA, Kunz-Schughart LA, Fuerst A, Mueller-Klieser W. J Cancer Res Clin Oncol. 2003 Jun;129(6):321-6. 

 

p53 expression and resistance against paclitaxel in patients with metastatic breast cancer.Schmidt M, Bachhuber A, Victor A, Steiner E, Mahlke M, Lehr HA, Pilch H, Weikel W, Knapstein PG. J Cancer Res Clin Oncol. 2003 May;129(5):295-302.

 

Multiple splice variants of lactate dehydrogenase C selectively expressed in human cancer.Koslowski M, Türeci O, Bell C, Krause P, Lehr HA, Brunner J, Seitz G, Nestle FO, Huber C, Sahin U. Cancer Res. 2002 Nov 15;62(22):6750-5.

 

Undetected malignancies of the breast: dynamic contrast-enhanced MR imaging at 1.0 T.Teifke A, Hlawatsch A, Beier T, Werner Vomweg T, Schadmand S, Schmidt M, Lehr HA, Thelen M. Radiology. 2002 Sep;224(3):881-8.

 

Thermal damage of the inner vein wall during endovenous laser treatment: key role of energy absorption by intravascular blood.Proebstle TM, Sandhofer M, Kargl A, Gül D, Rother W, Knop J, Lehr HA. Dermatol Surg. 2002 Jul;28(7):596-600.

 

Particulate matter contamination of intravenous antibiotics aggravates loss of functional capillary density in postischemic striated muscle.Lehr HA, Brunner J, Rangoonwala R, Kirkpatrick CJ. Am J Respir Crit Care Med. 2002 Feb 15;165(4):514-20.

 

Immunopathogenesis of atherosclerosis: endotoxin accelerates atherosclerosis in rabbits on hypercholesterolemic diet.Lehr HA, Sagban TA, Ihling C, Zähringer U, Hungerer KD, Blumrich M, Reifenberg K, Bhakdi S. Circulation. 2001 Aug 21;104(8):914-20.

 

Quantitative evaluation of HER-2/neu status in breast cancer by fluorescence in situ hybridization and by immunohistochemistry with image analysis.Lehr HA, Jacobs TW, Yaziji H, Schnitt SJ, Gown AM. Am J Clin Pathol. 2001 Jun;115(6):814-22.

 

Microcirculatory dysfunction induced by cigarette smoking.Lehr HA. Microcirculation. 2000 Dec;7(6 Pt 1):367-84. Review.

 

Cytokeratin 8 immunostaining pattern and E-cadherin expression distinguish lobular from ductal breast carcinoma. Lehr HA, Folpe A, Yaziji H, Kommoss F, Gown AM. Am J Clin Pathol. 2000 Aug;114(2):190-6.

 

Quantification of video-taped images in microcirculation research using inexpensive imaging software (Adobe Photoshop). Brunner J, Krummenauer F, Lehr HA.Microcirculation. 2000 Apr;7(2):103-7.

 

Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo.Atreya R, Mudter J, Finotto S, Müllberg J, Jostock T, Wirtz S, Schütz M, Bartsch B, Holtmann M, Becker C, Strand D, Czaja J, Schlaak JF, Lehr HA, Autschbach F, Schürmann G, Nishimoto N, Yoshizaki K, Ito H, Kishimoto T, Galle PR, Rose-John S, Neurath MF. Nat Med. 2000 May;6(5):583-8. Erratum in: Nat Med. 2010 Nov;16(11):1341. 

 

Assessment of proliferative activity in breast cancer: MIB-1 immunohistochemistry versus mitotic figure count.Lehr HA, Hansen DA, Kussick S, Li M, Hwang H, Krummenauer F, Trouet S, Gown AM. Hum Pathol. 1999 Nov;30(11):1314-20.

 

Polynitroxylated hemoglobin-based oxygen carrier: inhibition of free radical-induced microcirculatory dysfunction.Saetzler RK, Arfors KE, Tuma RF, Vasthare U, Ma L, Hsia CJ, Lehr HA. Free Radic Biol Med. 1999 Jul;27(1-2):1-6.

 

Pentobarbital-sensitive EDHF comediates ACh-induced arteriolar dilation in the hamster microcirculation.de Wit C, Esser N, Lehr HA, Bolz SS, Pohl U. Am J Physiol. 1999 May;276(5):H1527-34. doi: 10.1152/ajpheart.1999.276.5.H1527.

 

Intravital fluorescence microscopy for the study of leukocyte interaction with platelets and endothelial cells.Lehr HA, Vollmar B, Vajkoczy P, Menger MD. Methods Enzymol. 1999;300:462-81.

 

Do vitamin E supplements in diets for laboratory animals jeopardize findings in animal models of disease?Lehr HA, Vajkoczy P, Menger MD, Arfors KE. Free Radic Biol Med. 1999 Feb;26(3-4):472-81.

 

Complete chromogen separation and analysis in double immunohistochemical stains using Photoshop-based image analysis.Lehr HA, van der Loos CM, Teeling P, Gown AM. J Histochem Cytochem. 1999 Jan;47(1):119-26.

 

Application of photoshop-based image analysis to quantification of hormone receptor expression in breast cancer.Lehr HA, Mankoff DA, Corwin D, Santeusanio G, Gown AM. J Histochem Cytochem. 1997 Nov;45(11):1559-65.

 

Vitamin C blocks inflammatory platelet-activating factor mimetics created by cigarette smoking.Lehr HA, Weyrich AS, Saetzler RK, Jurek A, Arfors KE, Zimmerman GA, Prescott SM, McIntyre TM. J Clin Invest. 1997 May 15;99(10):2358-64.

 

Prevention of pancreatic islet xenograft rejection by dietary vitamin E.Vajkoczy P, Lehr HA, Hübner C, Arfors KE, Menger MD. Am J Pathol. 1997 Apr;150(4):1487-95.

Rationale for the use of antioxidant vitamins in clinical organ transplantation.Lehr HA, Messmer K. Transplantation. 1996 Nov 15;62(9):1197-9. Review. 

 

Wheat kernel ingestion protects from progression of muscle weakness in mdx mice, an animal model of Duchenne muscular dystrophy.Hübner C, Lehr HA, Bodlaj R, Finckh B, Oexle K, Marklund SL, Freudenberg K, Kontush A, Speer A, Terwolbeck K, Voit T, Kohlschütter A. Pediatr Res. 1996 Sep;40(3):444-9.

 

Protection from oxidized LDL-induced leukocyte adhesion to microvascular and macrovascular endothelium in vivo by vitamin C but not by vitamin E.Lehr HA, Frei B, Olofsson AM, Carew TE, Arfors KE. Circulation. 1995 Mar 1;91(5):1525-32.

 

Ischemia-reperfusion injury: enthusiasm in laboratory research but dilemma in clinical trials?Lehr HA, Menger MD, Granger DN.Circulation. 1994 Sep;90(3):1580.

 

 

P-selectin mediates the interaction of circulating leukocytes with platelets and microvascular endothelium in response to oxidized lipoprotein in vivo.Lehr HA, Olofsson AM, Carew TE, Vajkoczy P, von Andrian UH, Hübner C, Berndt MC, Steinberg D, Messmer K, Arfors KE. Lab Invest. 1994 Sep;71(3):380-6.

 

Vitamin C prevents cigarette smoke-induced leukocyte aggregation and adhesion to endothelium in vivo.Lehr HA, Frei B, Arfors KE. Proc Natl Acad Sci U S A. 1994 Aug 2;91(16):7688-92.

 

Mechanisms of tissue damage by leukocytes.Lehr HA, Arfors KE. Curr Opin Hematol. 1994 Jan;1(1):92-9. Review.

 

Scope and perspectives of intravital microscopy--bridge over from in vitro to in vivo.Menger MD, Lehr HA.Immunol Today. 1993 Nov;14(11):519-22. Review.

 

Adhesion-promoting effects of cigarette smoke on leukocytes and endothelial cells.Lehr HA. Ann N Y Acad Sci. 1993 May 28;686:112-8; discussion 118-9. Review. No abstract available. 

 

Hyperbaric oxygen treatment enhances the recovery of blood flow and functional capillary density in postischemic striated muscle.Sirsjö A, Lehr HA, Nolte D, Haapaniemi T, Lewis DH, Nylander G, Messmer K.Circ Shock. 1993 May;40(1):9-13.

 

Impact of leukocyte adhesion on myocardial ischemia/reperfusion injury: conceivable mechanisms and proven facts.Lehr HA, Menger MD, Messmer K. J Lab Clin Med. 1993 Apr;121(4):539-45. Review.

 

Dextran sulphate reduces diphenylhexatriene anisotropy in human peripheral blood lymphocytes: impact on plasma membrane fluidity and HIV-cytopathogenicity.Lehr HA, Zimmer JP, Hübner C, Reisinger EC, Kohlschütter A, Schmitz H. J Antimicrob Chemother. 1991 Nov;28(5):677-80.

 

Dietary fish oil reduces leukocyte/endothelium interaction following systemic administration of oxidatively modified low density lipoprotein.Lehr HA, Hübner C, Finckh B, Nolte D, Beisiegel U, Kohlschütter A, Messmer K. Circulation. 1991 Oct;84(4):1725-31.

 

Dietary fish oil blocks the microcirculatory manifestations of ischemia-reperfusion injury in striated muscle in hamsters.Lehr HA, Hübner C, Nolte D, Kohlschütter A, Messmer K. Proc Natl Acad Sci U S A. 1991 Aug 1;88(15):6726-30.

 

Role of leukotrienes in leukocyte adhesion following systemic administration of oxidatively modified human low density lipoprotein in hamsters.Lehr HA, Hübner C, Finckh B, Angermüller S, Nolte D, Beisiegel U, Kohlschütter A, Messmer K. J Clin Invest. 1991 Jul;88(1):9-14.

 

Leukotrienes as mediators in ischemia-reperfusion injury in a microcirculation model in the hamster. Lehr HA, Guhlmann A, Nolte D, Keppler D, Messmer K. J Clin Invest. 1991 Jun;87(6):2036-41.

 

Decreased binding of HIV-1 and vasoactive intestinal peptide following plasma membrane fluidization of CD4+ cells by phenytoin.Lehr HA, Zimmer JP, Hübner C, Ballmann M, Hachmann W, Vogel W, Baisch H, Hartter P, Albani M, Kohlschütter A, et al. Virology. 1990 Dec;179(2):609-17.

 

Effects of membrane lipid and fluidity modifications on HIV-1 infectibility of primate lymphocytes in vitro. Zimmer JP, Lehr HA, Hübner C, Lindner SG, Ramsperger R, Claussen M, Kohlschütter A, Schmitz H. Biosci Rep. 1990 Jun;10(3):263-70.

 

Decreased plasma membrane fluidity of peripheral blood lymphocytes after diethyldithiocarbamate (DTC) therapy in HIV-infected patients.Lehr HA, Zimmer JP, Hübner C, Reisinger EC, Kohlschütter A, Claussen M, Schmitz H, Dietrich M. Eur J Clin Pharmacol. 1989;37(5):521-3.

 

Diphenylhydantoin (DPH) blocks HIV-receptor on T-lymphocyte surface.Zimmer JP, Lehr HA, Kornhuber ME, Breitig D, Montagnier L, Gietzen K. Blut. 1986 Dec;53(6):447-50.

 

[Diphenylhydantoin in AIDS].Lehr HA, Zimmer JP, Kern W. Dtsch Med Wochenschr. 1986 Oct 31;111(44):1701. German. 

 

Management of a postbiopsy arterial pseudoaneurysm in a transplanted kidney: utilization of epsilon aminocaproic acid and controlled hypotension.Lehr HA, Waltzer WC, Anaise D, Rapaport FT. Transplant Proc. 1986 Aug;18(4):976-8.

 

[Diphenylhydantoin in the prevention and therapy of AIDS?].Lehr HA, Zimmer JP.Dtsch Med Wochenschr. 1986 Jun 20;111(25):1001-2. German.